Kit Rat Monoclonal Antibody [Clone ID: 2B8]

CAT#: TA320401

Rat Anti-Mouse CD117 (c-Kit) Purified (100 ug)

Product Images

Staining of C57BL/6 bone marrow cells with Anti-Human/Mouse CD45R (B220) FITC and 0.06 ug of Rat IgG2b kappa Isotype Control PE (left) or 0.125 ug of Anti-Mouse CD117 (c-Kit) PE (right). Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 2B8
• Applications: FC
• Recommended Dilution: Flow, IP
• Reactivities: Mouse, Pig
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: kit oncogene
• Database Link:
  NP_066922
  Entrez Gene 16590 Mouse
  UniProt ID P05532
• Background: The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.
• Synonyms: C-Kit; CD117; PBT; SCFR