Lgals3 Rat Monoclonal Antibody [Clone ID: eBioM3/38 (M3/38)]

CAT#: TA320412

Rat Anti-Human/Mouse Galectin-3 Purified (50 ug)

Product Images

Staining of mouse thioglycolate-induced peritoneal exudate cells (PECs) with 0.25 ug of Rat IgG2a K Isotype Control Purified (open histogram) or 0.25 ug of Anti-Human/Mouse Galectin-3 Purified (filled histogram) followed by F (ab')2 Anti-Rat IgG APC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: eBioM3/38 (M3/38)
• Applications: FC
• Recommended Dilution: Flow, ELISA, IHC, IP, WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lectin, galactose binding, soluble 3
• Database Link:
  NP_034835
  Entrez Gene 16854 Mouse
• Background: The eBioM3/38 antibody reacts with mouse Galectin-3 (Mac-2). Galectins are a family of animal lectins which appear to exhibit a variety of biological functions. Galectin 3 (aka LGALS3, galactose-specific soluble lectin 3, Mac-2, L-29) is one of the more extensively studied members of this family and is a 30 kDa beta-galactoside-binding protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homo-oligomerized. Galectin 3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.This monoclonal antibody eBioM3/38 crossreacts to human Galectin-3 (LGALS3).
• Synonyms: CBP35; GAL3; GALBP; GALIG; L-31; LGALS2; MAC-2; MAC2