LY75 Mouse Monoclonal Antibody [Clone ID: MG38]

CAT#: TA320417

Mouse Anti-Human CD205 Purified (25 ug)

Product Images

Staining of normal human peripheral blood cells (left) and mature dendritic cells (right) with Mouse IgG2b kappa Isotype Control Purified (open histogram) or 0.015 ug of Anti-Human CD205 Purified (filled histogram) followed by Anti-Mouse IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: MG38
• Applications: FC
• Recommended Dilution: Flow, IHC, IP
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lymphocyte antigen 75
• Database Link:
  NP_002340
  Entrez Gene 4065 Human
• Background: The MG38 monoclonal antibody reacts with human CD205, also known as DEC-205, an integral membrane protein homologous to the macrophage mannose receptor. CD205 is an endocytic dendritic receptor that mediates efficient processing and presentation of antigens on MHC class II productions in vivo. CD205 is highly expressed by dendritic cells (DCs) within the T cell areas of lymphoid tissues, particularly on CD8+ DCs that are believed to play a role in cross-priming. Expression of CD205 is detected with this antibody at high intensity on in vitro derived mature human DCs (mDC) and at intermediate intensity on immature human DCs (iDC). All leukocytes from peripheral blood show a degree of staining with this mAb that can be minimized by using very low concentrations of MG38.
• Synonyms: CD205; CLEC13B; DEC-205; GP200-MR6; LY-75

Reference Data

• Protein Families: Transmembrane