CD62E (SELE) Mouse Monoclonal Antibody [Clone ID: P2H3]

CAT#: TA320457

Mouse Anti-Human CD62E (E-Selectin) Purified (100 ug)

Product Images

Staining of TNF alpha-stimulated Human Umbilical Vein Endothelial Cells (HUVEC) with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human CD62E (E- Selectin) Purified (filled histogram) followed by F (ab')2 Anti-Mouse IgG PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: P2H3
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: selectin E
• Database Link:
  NP_000441
  Entrez Gene 6401 Human
  UniProt ID P16581
• Background: The P2H3 monoclonal antibody reacts with human CD62E, a 97-115 kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.
• Synonyms: CD62E; ELAM; ELAM1; ESEL; LECAM2

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)