CD62L (SELL) Mouse Monoclonal Antibody [Clone ID: DREG-56 (DREG56)]
Other products for "SELL"
Specifications
| Product Data | |
| Clone Name | DREG-56 (DREG56) |
| Applications | FC |
| Recommended Dilution | Flow, IHC, Functional Assay, WB |
| Reactivities | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
| Concentration | lot specific |
| Purification | Affinity purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | selectin L |
| Database Link | |
| Background | The DREG-56 monoclonal antibody reacts with human CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCAM-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues. |
| Synonyms | CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1 |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
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