CD62L (SELL) Mouse Monoclonal Antibody [Clone ID: DREG-56 (DREG56)]
Other products for "SELL"
Specifications
Product Data | |
Clone Name | DREG-56 (DREG56) |
Applications | FC |
Recommended Dilution | Flow, IHC, Functional Assay, WB |
Reactivities | Human |
Host | Mouse |
Clonality | Monoclonal |
Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | selectin L |
Database Link | |
Background | The DREG-56 monoclonal antibody reacts with human CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCAM-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues. |
Synonyms | CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
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