CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: AK-4]

CAT#: TA320460

Mouse Anti-Human CD62P (P-Selectin) Purified (100 ug)

Product Images

Staining of thrombin-activated human peripheral blood platelets with 0.5 ug of Mouse IgG1 kappa Isotype Control Purifed (open histogram) or 0.5 ug of Anti-Human CD62P (P-Selectin) Purified (filled histogram) followed by Anti-Mouse IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: AK-4
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: selectin P
• Database Link:
  NP_002996
  Entrez Gene 6403 Human
  UniProt ID P16109
• Background: The AK-4 monoclonal antibody reacts with human CD62P, a 140 kDa transmembrane glycoprotein also known as P-Selectin. Upon activation, CD62P is rapidly transported from its cytoplasmic stores in the Weibel-Palade bodies of endothelial cells or the alpha-granules of platelets to the surface. CD62P initiates the adhesive interaction between endothelial cells and neutrophils and monocytes during the inflammatory reaction and is also involved in the interaction of platelets with monocytes and neutrophils.
• Synonyms: CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)