SLC22A2 Rat Monoclonal Antibody [Clone ID: 9A2]

CAT#: TA320463

Rat Anti-Human/Mouse OCT2 Purified (25 ug)

Product Images

Ramos cell line lysates prepared under reducing conditions were resolved by SDS-PAGE then immunoblotted with 3 ug/ml of Anti-Human/Mouse OCT2 Purified. Bands were visualized using Anti-Rat IgG HRP.

Specifications

Product Data

• Clone Name: 9A2
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human, Mouse
• Host: Rat
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 22 member 2
• Database Link:
  NP_003049
  Entrez Gene 20518 MouseEntrez Gene 6582 Human
  UniProt ID O15244
• Background: This monoclonal 9A2 antibody recognizes human and mouse Oct2, a transcription factor that binds conserved octamer DNA motifs within immunoglobulin promoters. The structure of the Oct2 protein consists of an amino terminal glutamine-rich domain, a central POU homeodomain and a carboxy terminal transactivation domain. Predominantly expressed in the nucleus of B cells, Oct2 has also been found in activated T cells and a subset of myeloid cells. Based on knock-out studies, expression is not required for B cell commitment but is required for maturation. In addition to developmental expression, Oct2 has been associated with neoplasm and maybe a useful tool for characterization of DLBCL and classical Hodgkin?? disease.
• Synonyms: OCT2

Reference Data

• Protein Families: Transmembrane