STAT1 Hamster Monoclonal Antibody [Clone ID: ATO-2F5]

CAT#: TA320467

Hamster Anti-Human STAT1 Purified (25 ug)

Product Images

Immunoblot of human peripheral blood mononuclear cell (lane 1) and mouse splenocyte (lane 2) lysates with 2 ug/ml of Anti-Human STAT1 Purified. Bands were visualized using Anti-Armenian Hamster IgG HRP.

Specifications

Product Data

• Clone Name: ATO-2F5
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: signal transducer and activator of transcription 1
• Database Link:
  NP_009330
  Entrez Gene 6772 Human
  UniProt ID P42224
• Background: The ATO-2F5 monoclonal antibody reacts with human Stat-1 (Signal Transducer and Activator of transcription-1) and has shown some cross-reactivity to mouse Stat-1. Stat-1 is a ubiquitously expressed transcription factor that resides in the cytoplasm until interferon receptor signaling leads to JAK-mediated phosphorylation. Upon phosphorylation, Stat-1 dimerizes and translocates to the nucleus where it forms the ISGF3 (Interferon-Stimulated Gene Factor 3) complex with Stat-2 and IRF-9. This complex is the main transcriptional activator for interferon signaling.
• Synonyms: CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway