Tlr1 Rat Monoclonal Antibody [Clone ID: eBioLD5]

CAT#: TA320476

Rat Anti-Mouse CD281 (TLR1) Purified (25 ug)

Product Images

Left: Untransfected control (left) and mouse TLR1-transfected (right) Baf/3 cell lysates were loaded at 1x10e5 cells/lane, probed with 3 ug/mL Anti-Mouse CD281 (TLR1) Purified and revealed with HRP anti-rat IgG. Right: Peritoneal-exudate (left) and RAW264.7 (right) cell lysates were loaded at 1x10e5 cells/lane, probed with 3 ug/ml Anti-Mouse CD281 (TLR1) Purified and revealed with HRP anti-rat IgG.

Specifications

Product Data

• Clone Name: eBioLD5
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: toll-like receptor 1
• Database Link:
  NP_109607
  Entrez Gene 21897 Mouse
  UniProt ID Q9EPQ1
• Background: The eBioLD5 monoclonal antibody reacts with mouse Toll-like receptor 1 (TLR1, CD281). TLR1 is an approximately 98 kDa protein belonging to the Toll-like receptor family, and is closely-related to mouse TLR6 in both structure and function. Through the formation of a complex with TLR2, TLR1 is able to bind bacterially-derived triacyl lipopeptides, as well as soluble factors released from Neisseria meningitidis. TLR1 is expressed by macrophages and macrophages in TLR1-deficient mice display impaired production of inflammatory cytokines upon stimulation with triacyl lipopeptides and lipoproteins from mycobacteria.
• Synonyms: CD281; DKFZp547I0610; DKFZp564I0682; KIAA0012; MGC104956; MGC126311; MGC126312; rsc786; TIL