Vcam1 Mouse Monoclonal Antibody [Clone ID: eBioMR106 (MR106)]

CAT#: TA320510

Mouse Anti-Rat CD106 (VCAM-1) Purified (50 ug)

Product Images

Staining of rat bone marrow cells with 0.25 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.25 ug of Anti-Rat CD106 (VCAM-1) Purified (filled histogram) followed by Anti-Mouse IgG Biotin and Streptavidin PE. Cells in the large scatter population were used for analysis.

Specifications

Product Data

• Clone Name: eBioMR106 (MR106)
• Applications: FC
• Recommended Dilution: Flow, IHC, IP, WB
• Reactivities: Rat
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: vascular cell adhesion molecule 1
• Database Link:
  NP_035823
  Entrez Gene 25361 Rat
• Background: The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
• Synonyms: CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561