SYVN1 Goat Polyclonal Antibody

CAT#: TA321024

Goat Polyclonal Anti-SYVN1 Antibody

Product Images

SYVN1 antibody (2ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-3µg/ml
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: internal region of NP_115807.1; NP_757385.1 (HERQHLEARLQS)
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: synoviolin 1
• Database Link:
  NP_757385
  Entrez Gene 361712 RatEntrez Gene 483746 DogEntrez Gene 84447 Human
  UniProt ID Q86TM6
• Background: This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]
• Synonyms: DER3; HRD1
• Note: This antibody is expected to recognize isoforms a and b (NP_115807.1; NP_757385.1).

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Ubiquitin mediated proteolysis