Epoxide hydrolase (EPHX1) Rabbit Polyclonal Antibody

CAT#: TA321060

Anti-EPHX1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 106-455 amino acids of Human Epoxide hydrolase 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: epoxide hydrolase 1
• Database Link:
  NP_000111
  Entrez Gene 13849 MouseEntrez Gene 25315 RatEntrez Gene 2052 Human
  UniProt ID P07099
• Background: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of exogenous chemicals such as polycyclic aromatic hydrocarbons. Mutations in this gene cause preeclampsia; epoxide hydrolase deficiency or increased epoxide hydrolase activity.
• Synonyms: EPHX; EPOX; HYL1; MEH

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Metabolism of xenobiotics by cytochrome P450