KCNE1 Rabbit Polyclonal Antibody

CAT#: TA321082

Anti-KCNE1 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 15 kDa. Positive control: Mouse heart and testis tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane 1: Mouse heart tissue lysate Lane 2: Mouse testis tissue lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to N terminal 105 amino acids of human potassium voltage-gated channel, Isk-related family, member 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kDa
• Gene Name: potassium voltage-gated channel subfamily E regulatory subunit 1
• Database Link:
  NP_000210
  Entrez Gene 16509 MouseEntrez Gene 25471 RatEntrez Gene 3753 Human
  UniProt ID P15382
• Background: Voltage-gated potassium channels play a variety of important roles in human health and disease. KCNE1, also known as MinK, belongs to a family of small transmembrane proteins (KCNE1, 2, 3, 4, and KCNE1L) that modulate the activity of several voltage-gated K+ channels. KCNE1 functions as the modulatory β-subunit of the pore-forming a-subunit KCNQ1, and alters several biophysical properties of KCNQ1 channels. Research studies have shown that several inherited mutations in KCNE1 result in long QT syndrome and deafness.
• Synonyms: 5; ISK; JLNS; JLNS2; LQT2; LQT5; MinK

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane