alpha 1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody

CAT#: TA321105

Anti-SERPINA1 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human serum Primary antibody: TA321105 (SERPINA1 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321105 (SERPINA1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321105 (SERPINA1 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA321105 (SERPINA1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA321105 (SERPINA1 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human serum
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 290-303 amino acids of Human Alpha-1-antitrypsin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 47 kDa
• Gene Name: serpin family A member 1
• Database Link:
  NP_000286
  Entrez Gene 24648 RatEntrez Gene 5265 Human
  UniProt ID P01009
• Background: The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase; plasmin; thrombin; trypsin; chymotrypsin; and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
• Synonyms: A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Complement and coagulation cascades