TIMP3 Rabbit Polyclonal Antibody

CAT#: TA321115

Anti-TIMP3 Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Huvec cells Primary antibody: TA321115 (TIMP3 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321115 (TIMP3 Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321115 (TIMP3 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA321115 (TIMP3 Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA321115 (TIMP3 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Huvec cells
  IHC: 15-50
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 27-211 amino acids of human TIMP metallopeptidase inhibitor 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: TIMP metallopeptidase inhibitor 3
• Database Link:
  NP_000353
  Entrez Gene 21859 MouseEntrez Gene 25358 RatEntrez Gene 7078 Human
  UniProt ID P35625
• Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases; a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
• Synonyms: HSMRK222; K222; K222TA2; SFD

Reference Data

• Protein Families: Druggable Genome, Secreted Protein