beta 1 Adrenergic Receptor (ADRB1) Rabbit Polyclonal Antibody

CAT#: TA321176

Anti-ADRB1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human tonsil cancer tissue using TA321176 (ADRB1 Antibody) at dilution 1/25. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA321176 (ADRB1 Antibody) at dilution 1/25. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human tonsil cancer
  Predicted cell location: Cell membrane, Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 41-55 amino acids of Human Beta-1 adrenergic receptor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adrenoceptor beta 1
• Database Link:
  NP_000675
  Entrez Gene 11554 MouseEntrez Gene 24925 RatEntrez Gene 153 Human
  UniProt ID P08588
• Background: The adrenergic receptors (subtypes alpha 1; alpha 2; beta 1; and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
• Synonyms: ADRB1R; B1AR; BETA1AR; RHR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Dilated cardiomyopathy, Endocytosis, Gap junction, Neuroactive ligand-receptor interaction