ITGB6 Rabbit Polyclonal Antibody
Other products for "ITGB6"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 50-300 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Cell membrane |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 139-434 amino acids of human integrin, beta 6 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | integrin subunit beta 6 |
Database Link | |
Background | Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. Integrin; beta 6 has been shown to interact with FHL2. Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. |
Synonyms | AI1H |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.