PTGS1 Rabbit Polyclonal Antibody

CAT#: TA321245

Anti-PTGS1 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 69 kDa. Positive control: NIH/3T3 and 293T cell lysate. Recommended dilution: 1/ 100-500. (Gel: 8%SDS-PAGE Lane 1: NIH/3T3 cell lysate Lane 2: 293T cell lysate Lysates: 30 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:200-1000, WB: 1:100-500
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide (KLH-coupled) derived from human PTGS1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: prostaglandin-endoperoxide synthase 1
• Database Link:
  NP_000953
  Entrez Gene 19224 MouseEntrez Gene 5742 Human
  UniProt ID P23219
• Background: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
• Synonyms: COX1; COX3; HS; PCOX1; PES-1; PGG; PGHS-1; PGHS1; PHS1; PTGHS

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways