PTGS1 Rabbit Polyclonal Antibody

CAT#: TA321246

Anti-PTGS1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 20-100
Positive control: Human stomach cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 586-599 amino acids of Human prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name prostaglandin-endoperoxide synthase 1
Background Cyclooxygenase-1 (COX-1); also known as prostaglandin G/H synthase 1; prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1; is an enzyme that in humans is encoded by the PTGS1 gene. This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells; and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Synonyms COX1; COX3; HS; PCOX1; PES-1; PGG; PGHS-1; PGHS1; PHS1; PTGHS
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Arachidonic acid metabolism, Metabolic pathways

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