OPCML Rabbit Polyclonal Antibody

CAT#: TA321261

Anti-OPCML Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Mouse brain tissue Primary antibody: TA321261 (OPCML Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 28-322 amino acids of human opioid binding protein/cell adhesion molecule-like
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: opioid binding protein/cell adhesion molecule-like
• Database Link:
  NP_001012393
  Entrez Gene 116597 RatEntrez Gene 330908 MouseEntrez Gene 4978 Human
  UniProt ID Q14982
• Background: This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids; exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution; it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: IGLON1; OBCAM; OPCM

Reference Data

• Protein Families: Druggable Genome, Transmembrane