EDG1 (S1PR1) Rabbit Polyclonal Antibody

CAT#: TA321340

Anti-S1PR1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 359-372 amino acids of human sphingosine-1-phosphate receptor 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: sphingosine-1-phosphate receptor 1
• Database Link:
  NP_001391
  Entrez Gene 13609 MouseEntrez Gene 29733 RatEntrez Gene 1901 Human
  UniProt ID P21453
• Background: The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity; and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.
• Synonyms: CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction