GFR alpha 3 (GFRA3) Rabbit Polyclonal Antibody

CAT#: TA321357

Anti-GFRA3 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-3000
  WB positive control: Human fetal kidney and brain tissue
  IHC: 20-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 346-359 amino acids of Human GDNF family receptor alpha 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44 kDa
• Gene Name: GDNF family receptor alpha 3
• Database Link:
  NP_001487
  Entrez Gene 14587 MouseEntrez Gene 84422 RatEntrez Gene 2676 Human
  UniProt ID O60609
• Background: GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand; artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system; but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues; particularly those of the digestive and urogenital systems; but high expression in stomach and appendix. Several types of glandular tissues show low expression.
• Synonyms: GDNFR3

Reference Data

• Protein Families: Druggable Genome