GFR alpha 3 (GFRA3) Rabbit Polyclonal Antibody

CAT#: TA321358

Anti-GFRA3 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 50-150
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm, Cell membrane
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 346-359 amino acids of Human GDNF family receptor alpha 3
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name GDNF family receptor alpha 3
Background GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand; artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system; but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues; particularly those of the digestive and urogenital systems; but high expression in stomach and appendix. Several types of glandular tissues show low expression.
Synonyms GDNFR3
Reference Data
Protein Families Druggable Genome

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