GFR alpha 3 (GFRA3) Rabbit Polyclonal Antibody
Other products for "GFRA3"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 50-150 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm, Cell membrane |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 346-359 amino acids of Human GDNF family receptor alpha 3 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | GDNF family receptor alpha 3 |
Database Link | |
Background | GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand; artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system; but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues; particularly those of the digestive and urogenital systems; but high expression in stomach and appendix. Several types of glandular tissues show low expression. |
Synonyms | GDNFR3 |
Reference Data | |
Protein Families | Druggable Genome |
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