IL13 receptor alpha 1 (IL13RA1) Rabbit Polyclonal Antibody

CAT#: TA321373

Anti-IL13RA1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Mouse heart tissue, 293T cell lysates
  IHC: 100-200
  Positive control: Human esophagus cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 25-363 amino acids of Human Interleukin 13 receptor, alpha 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 13 receptor subunit alpha 1
• Database Link:
  NP_001551
  Entrez Gene 16164 MouseEntrez Gene 252963 RatEntrez Gene 3597 Human
  UniProt ID P78552
• Background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha; a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor; and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2; and thus may mediate the signaling processes that lead to the activation of JAK1; STAT3 and STAT6 induced by IL13 and IL4.
• Synonyms: CD213A1; CT19; IL-13Ra; NR4

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway