PARP1 Rabbit Polyclonal Antibody

CAT#: TA321380

Anti-PARP1 Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

Other products for "PARP1"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Hela, K562 and Jurkat cells
IHC: 50-200
Positive control: Human ovarian cancer
Predicted cell location: Nucleus
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 12-21 amino acids of human poly (ADP-ribose) polymerase 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 113 kDa
Gene Name poly(ADP-ribose) polymerase 1
Background This gene encodes a chromatin-associated enzyme; poly(ADP-ribosyl)transferase; which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation; proliferation; and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition; this enzyme may be the site of mutation in Fanconi anemia; and may participate in the pathophysiology of type I diabetes.
Synonyms ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Base excision repair

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.