Ferritin Heavy Chain (FTH1) Rabbit Polyclonal Antibody

CAT#: TA321426

Anti-FTH1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 100-300
Positive control: Human ovarian cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name ferritin heavy chain 1
Background This gene encodes the heavy subunit of ferritin; the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed; but their biological validity has not been determined.
Synonyms FHC; FTH; FTHL6; HFE5; PIG15; PLIF
Reference Data
Protein Families Druggable Genome
Protein Pathways Porphyrin and chlorophyll metabolism

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