VEGF Receptor 2 (KDR) Rabbit Polyclonal Antibody

CAT#: TA321460

Anti-KDR (phospho-Tyr1059) Rabbit Polyclonal Antibody

Product Images

Predicted band size: 152 kDa. Positive control: HT29 cells treated with SCF-1 lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane 1: HT29 cells untreated with SCF-1 lysate Lane 2: HT29 cells treated with SCF-1 lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide sequence around phosphorylation site of tyrosine 1059 (P-D-Y(p)-V-R)derived from Human VEGFR2.
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 152 kDa
• Gene Name: kinase insert domain receptor
• Database Link:
  NP_002244
  Entrez Gene 16542 MouseEntrez Gene 3791 Human
  UniProt ID P35968
• Background: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
• Synonyms: CD309; FLK1; VEGFR; VEGFR2

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway