BNP (NPPB) Rabbit Polyclonal Antibody

CAT#: TA321494

Anti-NPPB Rabbit Polyclonal Antibody

Product Images

Predicted band size: 15 kDa. Positive control: Human plasma tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kDa
• Gene Name: natriuretic peptide B
• Database Link:
  NP_002512
  Entrez Gene 4879 Human
  UniProt ID P16860
• Background: B-type natriuretic peptide (BNP) is a cardiac neurohormone specifically secreted from the ventricles in response to volume expansion and pressure overload. The actions of BNP include natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is also found to help restore the body's salt and water balance and improve heart function. BNP is co-secreted along with a biologically inactive N-terminal fragment (NT-proBNP). Circulating BNP and NT-proBNP provide important information on cardiac dysfunction, hypervolemia, and risk in patients with severe impairment of kidney function.
• Synonyms: BNP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Stem cell - Pluripotency