BNP (NPPB) Rabbit Polyclonal Antibody

CAT#: TA321495

Anti-NPPB Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Secreted
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 77-90 amino acids of Human natriuretic peptide B
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: natriuretic peptide B
• Database Link:
  NP_002512
  Entrez Gene 18158 MouseEntrez Gene 25105 RatEntrez Gene 4879 Human
  UniProt ID P16860
• Background: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events; one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis; diuresis; vasorelaxation; inhibition of renin and aldosterone secretion; and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
• Synonyms: BNP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Stem cell - Pluripotency