Parathyroid hormone related protein (PTHLH) Rabbit Polyclonal Antibody

CAT#: TA321533

Anti-PTHLH Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321533 (PTHLH Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321533 (PTHLH Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321533 (PTHLH Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321533 (PTHLH Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 37-177 amino acids of human parathyroid hormone-like hormone
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: parathyroid hormone-like hormone
• Database Link:
  NP_002811
  Entrez Gene 19227 MouseEntrez Gene 24695 RatEntrez Gene 5744 Human
  UniProt ID P12272
• Background: The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone; PTHR1; is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites; in-frame and downstream of the initiator AUG codon; to give rise to nuclear forms of this hormone.
• Synonyms: BDE2; HHM; PLP; PTHR; PTHRP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein