ADAM17 Rabbit Polyclonal Antibody

CAT#: TA321563

Anti-ADAM17 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Jurkat, Raji, Hela, K562, 293T cell lysates
IHC: 50-200
Positive control: Human breast cancer
Predicted cell location: Cytoplasm and Cell membrane
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name ADAM metallopeptidase domain 17
Background This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.?
Synonyms ADAM18; CD156B; CSVP; NISBD; NISBD1; TACE
Reference Data
Protein Families Druggable Genome, Protease, Transmembrane
Protein Pathways Alzheimer's disease, Epithelial cell signaling in Helicobacter pylori infection, Notch signaling pathway

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