TRPC3 Rabbit Polyclonal Antibody

CAT#: TA321569

Anti-TRPC3 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 97 kDa. Positive control: Human fetal brain tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/1600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes)

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  Predicted cell location: Cytoplasm or Nucleus. Positive control: Human lung cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using TRPC3 antibody at dilution 1/80, on the right is treated with the synthetic peptide. (Original magnification:x200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:2000-10000, WB: 1:1000-5000,IHC: 1:100-300
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 834-846 amino acids of human transient receptor potential cation channel, subfamily C, member 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 97 kDa
• Gene Name: transient receptor potential cation channel subfamily C member 3
• Database Link:
  NP_003296
  Entrez Gene 22065 MouseEntrez Gene 60395 RatEntrez Gene 7222 Human
  UniProt ID Q13507
• Background: The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: SCA41; TRP3

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane