HMGA2 Rabbit Polyclonal Antibody

CAT#: TA321583

Anti-HMGA2 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of Human gliomas tissue using TA321583 (HMGA2 Antibody) at dilution 1/150

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1000-5000, WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 59-72 amino acids of Human high mobility group AT-hook 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 12 kDa
• Gene Name: high mobility group AT-hook 2
• Database Link:
  NP_003474
  Entrez Gene 15364 MouseEntrez Gene 84017 RatEntrez Gene 8091 Human
  UniProt ID P52926
• Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion; amplification; and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants; encoding different isoforms; have been characterized
• Synonyms: BABL; HMGI-C; HMGIC; LIPO; STQTL9

Reference Data

• Protein Families: Druggable Genome