CES2 Rabbit Polyclonal Antibody

CAT#: TA321606

Anti-CES2 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 62 kDa. Positive control: SW620 cell and liver tissue lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lane 1: SW620 cell lysate Lane 2: Liver tissue lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 355-369 amino acids of human carboxylesterase 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: carboxylesterase 2
• Database Link:
  NP_003860
  Entrez Gene 100910144 RatEntrez Gene 8824 Human
  UniProt ID O00748
• Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: CE-2; CES2A1; iCE; PCE-2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - other enzymes