HDAC3 Rabbit Polyclonal Antibody

CAT#: TA321609

Anti-HDAC3 Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

Product Images

Other products for "HDAC3"

Specifications

Product Data
Applications WB
Recommended Dilution WB: 200-1000
WB positive control: A549, NIH/3T3, Raji, 293T and Hela cells
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 414-428 amino acids of Human histone deacetylase 3
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 49 kDa
Gene Name histone deacetylase 3
Background Histones play a critical role in transcriptional regulation; cell cycle progression; and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Synonyms HD3; RPD3; RPD3-2
Reference Data
Protein Families Druggable Genome, Transcription Factors

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.