Ephrin A1 (EFNA1) Rabbit Polyclonal Antibody

CAT#: TA321655

Anti-EFNA1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 50-150
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 19-205 amino acids of human ephrin-A1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ephrin A1
• Database Link:
  NP_004419
  Entrez Gene 13636 MouseEntrez Gene 94268 RatEntrez Gene 1942 Human
  UniProt ID P20827
• Background: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events; especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships; ephrins are divided into the ephrin-A (EFNA) class; which are anchored to the membrane by a glycosylphosphatidylinositol linkage; and the ephrin-B (EFNB) class; which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2; EPHA4; EPHA5; EPHA6; and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
• Synonyms: B61; ECKLG; EFL1; EPLG1; LERK-1; LERK1; TNFAIP4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance