VNN1 Rabbit Polyclonal Antibody

CAT#: TA321664

Anti-VNN1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IF
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 483-496 amino acids of human vanin 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: vanin 1
• Database Link:
  NP_004657
  Entrez Gene 22361 MouseEntrez Gene 29142 RatEntrez Gene 8876 Human
  UniProt ID O95497
• Background: This gene encodes a member of the vanin family of proteins; which share extensive sequence similarity with each other; and also with biotinidase. The family includes secreted and membrane-associated proteins; a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins; however; they possess pantetheinase activity; which may play a role in oxidative-stress response. This protein; like its mouse homolog; is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to; and in the same transcriptional orientation as; two other vanin genes on chromosome 6q23-q24.
• Synonyms: HDLCQ8; Tiff66

Reference Data

• Protein Pathways: Pantothenate and CoA biosynthesis