EDG4 (LPAR2) Rabbit Polyclonal Antibody

CAT#: TA321666

Anti-LPAR2 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 340-351 amino acids of human lysophosphatidic acid receptor 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lysophosphatidic acid receptor 2
• Database Link:
  NP_004711
  Entrez Gene 53978 MouseEntrez Gene 498609 RatEntrez Gene 9170 Human
  UniProt ID Q9HBW0
• Background: This gene encodes a member of family I of the G protein-coupled receptors; as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization; a critical cellular response to LPA in cells; through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined.
• Synonyms: EDG-4; EDG4; LPA-2; LPA2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction