GDF15 Rabbit Polyclonal Antibody

CAT#: TA321673

Anti-GDF15 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1:1000-5000, WB: 1:200-1000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 195-308 amino acids of human growth differentiation factor 15
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 34 kDa
Gene Name growth differentiation factor 15
Background Bone morphogenetic proteins (e.g.; BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF15 mRNA is most abundant in the liver; with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver; kidney; heart and lung.
Synonyms GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB
Reference Data
Protein Families Druggable Genome, Secreted Protein

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