Aquaporin 3 (AQP3) Rabbit Polyclonal Antibody

CAT#: TA321677

Anti-AQP3 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human colorectal cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 278-292 amino acids of Human Aquaporin-3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: aquaporin 3 (Gill blood group)
• Database Link:
  NP_004916
  Entrez Gene 11828 MouseEntrez Gene 65133 RatEntrez Gene 360 Human
  UniProt ID Q92482
• Background: This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein; also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function; aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol; but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
• Synonyms: AQP-3; GIL

Reference Data

• Protein Families: Druggable Genome, Transmembrane