PODXL Rabbit Polyclonal Antibody

CAT#: TA321710

Anti-PODXL Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm, Apical Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 345-357 amino acids of Human podocalyxin-like
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: podocalyxin like
• Database Link:
  NP_005388
  Entrez Gene 27205 MouseEntrez Gene 192181 RatEntrez Gene 5420 Human
  UniProt ID O00592
• Background: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements; playing a role in hematopoetic cell differentiation; and being expressed in vascular endothelium cells and binding to L-selectin.
• Synonyms: Gp200; PC; PCLP; PCLP-1

Reference Data

• Protein Families: Transmembrane