ACTR1A Rabbit Polyclonal Antibody

CAT#: TA321724

Anti-ACTR1A Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321724 (ACTR1A Antibody) at dilution 1/75 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321724 (ACTR1A Antibody) at dilution 1/75, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-100
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ARP1 actin-related protein 1 homolog A, centractin alpha
• Database Link:
  NP_005727
  Entrez Gene 54130 MouseEntrez Gene 294010 RatEntrez Gene 10121 Human
  UniProt ID P61163
• Background: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.?
• Synonyms: ARP1; Arp1A; CTRN1