Melatonin Receptor 1A (MTNR1A) Rabbit Polyclonal Antibody

CAT#: TA321735

Anti-MTNR1A Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: SP20 cell lysate
IHC: 30-150
Positive control: Human colorectal cancer
Predicted cell location: Cell membrane
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide peptide corresponding to a region derived from 130-144 amino acids of human melatonin receptor 1A
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 39 kDa
Gene Name melatonin receptor 1A
Background This gene encodes one of two high affinity forms of a receptor for melatonin; the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled; 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Synonyms MEL-1A-R; MT1
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.