NDRG1 Rabbit Polyclonal Antibody

CAT#: TA321744

Anti-NDRG1 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Human lymphoma tissue Primary antibody: TA321744 (NDRG1 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 minutes

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA321744 (NDRG1 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA321744 (NDRG1 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA321744 (NDRG1 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA321744 (NDRG1 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human lymphoma tissue
  IHC: 50-200
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 381-394 amino acids of human N-myc downstream regulated 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: N-myc downstream regulated 1
• Database Link:
  NP_006087
  Entrez Gene 17988 MouseEntrez Gene 299923 RatEntrez Gene 10397 Human
  UniProt ID Q92597
• Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses; hormone responses; cell growth; and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D; and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5