Kallikrein 5 (KLK5) Rabbit Polyclonal Antibody

CAT#: TA321822

Anti-KLK5 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Mouse brain tissue
  IHC: 100-300
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 279-293 amino acids of Human kallikrein-related peptidase 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: kallikrein related peptidase 5
• Database Link:
  NP_036559
  Entrez Gene 68668 MouseEntrez Gene 102546758 RatEntrez Gene 690603 RatEntrez Gene 25818 Human
  UniProt ID Q9Y337
• Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.?
• Synonyms: KLK-L2; KLKL2; SCTE

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane