SOCS5 Rabbit Polyclonal Antibody

CAT#: TA321826

Anti-SOCS5 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human suppressor of cytokine signaling 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: suppressor of cytokine signaling 5
• Database Link:
  NP_054730
  Entrez Gene 56468 MouseEntrez Gene 500616 RatEntrez Gene 9655 Human
  UniProt ID O75159
• Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family; also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
• Synonyms: CIS6; Cish5; CISH6; SOCS-5

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Jak-STAT signaling pathway