PPAR gamma (PPARG) Rabbit Polyclonal Antibody

CAT#: TA321842

Anti-PPARG Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1-15 amino acids of Human peroxisome proliferator-activated receptor gamma
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: peroxisome proliferator activated receptor gamma
• Database Link:
  NP_005028
  Entrez Gene 19016 MouseEntrez Gene 25664 RatEntrez Gene 5468 Human
  UniProt ID P37231
• Background: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha; PPAR-delta; and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally; PPAR-gamma has been implicated in the pathology of numerous diseases including obesity; diabetes; atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
• Synonyms: CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer