Relaxin 3 receptor 1 (RXFP3) Rabbit Polyclonal Antibody

CAT#: TA321853

Anti-RXFP3 rabbit polyclonal antibody

Product Images

Predicted band size: 51 kDa. Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes)

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  Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer using RXFP3 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification: x 200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1000-2000, WB: 1:200-1000, IHC: 1:25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 456-468 amino acids of human relaxin/insulin-like family peptide receptor 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: relaxin/insulin like family peptide receptor 3
• Database Link:
  NP_057652
  Entrez Gene 239336 MouseEntrez Gene 294807 RatEntrez Gene 51289 Human
  UniProt ID Q9NSD7
• Background: Relaxin/insulin-like family peptide receptor 3, also known as?RXFP3, is a human?G-protein coupled receptor. Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
• Synonyms: GPCR135; RLN3R1; RXFPR3; SALPR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane