GRASP1 (GRIPAP1) Rabbit Polyclonal Antibody

CAT#: TA321870

Anti-GRIPAP1 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 96 kDa. Positive control: Rat brain and mouse brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane 1, 2: Rat brain and mouse brain tissue lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 96 kDa
• Gene Name: GRIP1 associated protein 1
• Database Link:
  NP_064522
  Entrez Gene 54645 MouseEntrez Gene 116493 RatEntrez Gene 56850 Human
  UniProt ID Q4V328
• Background: GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid protein encoded by the human gene GRASP . GRASP is a scaffold protein that com- prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipper region and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.
• Synonyms: GRASP-1

Reference Data

• Protein Families: Druggable Genome