RAB18 Rabbit Polyclonal Antibody

CAT#: TA321890

Anti-RAB18 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Mouse heart tissue Primary antibody: TA321890 (RAB18 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321890 (RAB18 Antibody) at dilution 1/300 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321890 (RAB18 Antibody) at dilution 1/300, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse heart tissue
  IHC: 200-500
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 128-141 amino acids of Human Ras-related protein Rab-18
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: RAB18, member RAS oncogene family
• Database Link:
  NP_067075
  Entrez Gene 19330 MouseEntrez Gene 307039 RatEntrez Gene 22931 Human
  UniProt ID Q9NP72
• Background: The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: RAB18LI1; WARBM3

Reference Data

• Protein Families: Druggable Genome